Lead Synthetic Chemist - Pharmaceutical Research

About the Role

Our client, a distinguished leader in Scientific Research & Development, is actively seeking an experienced Lead Synthetic Chemist to spearhead their pharmaceutical research initiatives in Mahikeng, North West . This pivotal role requires a highly skilled organic chemist with a proven track record in designing and executing complex synthetic routes for novel drug candidates. You will lead a team of chemists, manage laboratory operations, and collaborate closely with pharmacologists and biologists to advance therapeutic discoveries. This position offers a unique opportunity to contribute to life-saving medications within a state-of-the-art research facility, making a tangible impact on global health. The successful candidate must possess exceptional expertise in synthetic organic chemistry and a strong drive for innovation.

Key Responsibilities

• Lead the design and execution of multi-step synthetic routes for complex organic molecules, with a focus on potential pharmaceutical agents.
• Develop and optimize synthetic methodologies to improve efficiency, yield, and purity of target compounds.
• Oversee and mentor a team of synthetic chemists, guiding their research projects and ensuring high-quality experimental work.
• Perform rigorous characterization of synthesized compounds using techniques such as NMR, Mass Spectrometry, HPLC, and IR spectroscopy.
• Manage laboratory inventory, equipment maintenance, and adherence to all safety protocols.
• Collaborate with medicinal chemists, pharmacologists, and biologists to support drug discovery programs.
• Stay abreast of the latest developments in synthetic organic chemistry and medicinal chemistry through literature review and conferences.
• Contribute to patent applications and scientific publications detailing synthetic strategies and outcomes.

Requirements

• Ph.D. in Organic Chemistry or Synthetic Chemistry.
• A minimum of 6 years of post-doctoral or industry experience in synthetic organic chemistry, with a significant focus on drug discovery or pharmaceutical research.
• Demonstrated expertise in designing and executing complex total synthesis and methodology development.
• Proficiency in modern spectroscopic and chromatographic techniques for compound characterization and purification.
• Strong understanding of reaction mechanisms, stereochemistry, and protecting group strategies.
• Proven leadership experience, with the ability to manage and motivate a team of chemists.
• Excellent problem-solving skills and a meticulous approach to experimental work.
• Strong written and verbal communication skills, essential for technical reporting and team collaboration.
• Experience working in a regulated environment (e.g., GMP) is a plus.

Benefits

Our client provides a highly competitive salary package, comprehensive health benefits, retirement savings plans, and performance-based bonuses. Employees have access to advanced laboratory facilities and cutting-edge research equipment. Opportunities for professional development, including conference attendance and training, are actively supported. The company fosters a collaborative and innovative work culture in Mahikeng, North West . This role offers the chance to make significant contributions to pharmaceutical innovation and career growth.

#J-18808-Ljbffr