Senior Laboratory Specialist (P001260) Readvertisement
North West UniversityPotchefstroom, North West, South Africa3 days ago
Job descriptionThe Senior Laboratory Specialist is responsible for ensuring excellence in research operations and scientific output through comprehensive oversight of technical infrastructure, training initiatives, and research activities. This role entails overseeing the maintenance and operation of high-value analytical instrumentation by technical staff and students, thereby enhancing operational efficiency, reducing repair costs, and maximising research productivity. Concurrently, the Senior Lab Specialist leads the development and implementation of standardised, high-quality operating procedures and training programs for routine and advanced analytical methodologies. The role provides scientific consultation across all research phases, including experimental design, statistical methodology, data analysis, and quality control, to uphold consistency, accuracy, and scientific rigor. Additionally, the role involves leading external collaborative research projects, thereby fostering the internationalisation of the research entity and driving increased publication output. By integrating technical leadership with scientific expertise, the Senior Lab Specialist plays a pivotal role in maintaining a high-performing, globally connected research environment. Supervise technical staff in daily operation, maintenance and troubleshooting of high-value analytical instrumentation. Develop and enforce preventative maintenance schedules to minimise downtime / repair costs. Optimise resource allocation and lab scheduling, prioritising high-impact projects. Drive development / optimisation of analytical methods and improve data quality control and reproducibility. Provide scientific consultation : advise on study design, sample preparation, method selection, data processing / statistical analysis, and quality control. Co‑develop and maintain standardised data processing pipelines. Lead / foster collaborative research projects (national / international); co‑author publications to increase output and internationalisation. Student training and post‑graduate (MSc and PhD) supervision. Design high‑quality, standardised training programs for technical staff and students to promote quality control and regulatory practices. Identify and facilitate external training opportunities when needed to align with industry standards. Effective and efficient inventory management and procurement to align with research priorities. Maintain rigorous oversight of laboratory record‑keeping by ensuring regular and compliant logbook entries. Build and maintain strong relationships with application specialists and representatives to maximise technical support and drive innovation in laboratory practices. Adhering to ISO 17025 / Good Laboratory Practice (GLP) standards where applicable. Drive continuous improvement in lab processes and data quality. Lead the development, implementation and maintenance of quality management systems, including SOPs for all lab processes, data integrity checks, and regular internal audits. As directed by the Director. Foster a safety‑focused culture by encouraging proactive risk identification, reporting, and shared accountability within the lab team (GLP, OHS and ethical research practices). A PhD (NQF level 10) in Biochemistry or Analytical Chemistry. A minimum of 5 years’ experience in the following areas : Gas‑ and liquid chromatography mass spectrometry (GC‑MS and LC‑MS); Nuclear magnetic resonance (NMR); Bioenergetics and metabolic flux analysis (Seahorse XF and / or Oroboros O2k); Human and animal metabolomics and bioenergetics; and Data processing and statistical analysis A minimum of 2 years’ experience in the supervision / co‑supervision of post‑graduate students. Any academic qualification in Statistics with Biostatistics as an area of specialisation. Registration with the South African Council for Natural Scientific Professions (SACNASP). Membership with professional bodies such as South African Association for Mass Spectrometry (SAAMS), Chromatography Society of South Africa (ChromSA) or Metabolomics South Africa (MSA). Advanced knowledge of gas chromatography‑mass spectrometry (GC‑MS) – application, maintenance, method development, method validation, quality control. Advanced knowledge of liquid chromatography‑mass spectrometry (LC‑MS) – application, maintenance, method development, method validation, quality control. Advanced knowledge of nuclear magnetic resonance (NMR) – application, maintenance, method development, method validation, quality control. Advanced knowledge of bioenergetics and metabolic flux analysis (Seahorse XF / Oroboros) – application, maintenance, method development, method validation, quality control. Proven ability to derive robust biological insights from metabolomics and bioenergetics data through rigorous preprocessing and application of advanced statistical methods. Skilled in sample preparation for diverse metabolomics platforms and bioenergetic analyses spanning cells, animal models, and human specimens. Excellent computer skills with proven competency in mass spectrometric (MS), NMR, respirometry and metabolic flux software and data processing. Record keeping of equipment booking, usage logs, results and quality documentation. Strong analytical and problem‑solving skills. Language proficient in a multi‑lingual environment. Strong publication record in metabolomics and bioenergetics research, underpinned by advanced knowledge in mammalian metabolic biochemistry. Experience in post‑graduate supervision. Ability to design and deliver effective training programs for staff and students, fostering skill development in lab techniques, safety practices, and adherence to regulatory standards. Ability to effectively work independently and in a team. Exceptional attention to detail and consistency in executing complex tasks. Ability to function under pressure. Natural innovator who strives for ‘best practice’ and technical advancement. Ability to build good interpersonal relationships and communicate effectively across diverse teams, fostering trust and facilitating knowledge exchange.
Job title : Senior Laboratory Specialist (P ) Readvertisement
Job Location : North West, Potchefstroom
Deadline : November 30, 2025
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Job description
PURPOSE OF THE POSITION
KEY RESPONSIBILITIES
Operational activities
Research and Innovation
Teaching and Learning
Laboratory Administration
Quality control
Ad hoc tasks
Occupational Health and Safety
Minimum requirements
Basic laboratory skills and management;
RECOMMENDATIONS / ADDED ADVANTAGES
KEY FUNCTIONAL / TECHNICAL COMPETENCIES
BEHAVIOURAL COMPETENCIES
Apply by : 21 November 2025
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Specialist Laboratory • Potchefstroom, North West, South Africa
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