Postdoctoral Researcher, Molecular Basis of Sensory Mechanotransduction (m / f / d)

Overview

The Max Delbrück Center for Molecular Medicine in the Helmholtz Association aims to transform tomorrow’s medicine through our discoveries of today. At locations in Berlin-Buch, Berlin-Mitte, Heidelberg and Mannheim, our scientists collaborate across disciplines to unravel the complexities of disease at the systems level – from molecules and cells to organs and entire organisms. Through strong academic, clinical, and industry partnerships, as well as global networks, we translate biological insights into innovations for early detection, individualized therapies, and disease prevention. Founded in 1992, the Max Delbrück Center is home to a vibrant community of 1,800 people from more than 70 countries.

The research group of Prof. Gary Lewin at the Max Delbrück Center for Molecular Medicine (MDC) is seeking a Postdoctoral Researcher (m / f / d) to study the molecular mechanisms of somatic sensation. Our goal is to understand how mechanical stimuli, such as touch or pressure, are detected by nerve cells and converted into electrical signals. We identify and characterize the molecular components involved in this transduction process using state-of-the-art molecular biology, electrophysiology, and biophysical techniques. We are looking for a motivated and experimentally driven scientist with a strong interest in interdisciplinary research. Experience in electrophysiology, molecular biology, or biophysics is an advantage. The successful candidate will apply molecular, imaging, and electrophysiological methods to investigate the molecular mechanisms of somatic mechanotransduction. We use genetic mouse models and human cells to gain insights that contribute to a better understanding and potential treatment of human diseases.

Responsibilities

• Conduct electrophysiological studies on mechanotransduction molecules using mouse models and heterologous expression systems
• Apply and further develop molecular biological, imaging, and biophysical methods to characterize the function of mechanosensitive ion channels
• Analyze cellular signaling mechanisms involved in the conversion of mechanical stimuli
• Collaborate with internal and external partners within an interdisciplinary research team
• Present and publish scientific results at conferences and in peer-reviewed journals

Qualifications

We Offer / Benefits

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